147 research outputs found
Eco-visualisation: Combining art and technology to reduce energy consumption
Artworks that display the real time usage of key resources such as electricity
offer new strategies to conserve energy. These eco-visualisations-or artworks that
creatively visualise ecologically significant data in real time-represent a substantial
contribution to new knowledge about dynamic feedback as a tool to promote energy
conservation and environmental site-based learning in this interdisciplinary project that
expands and builds on prior findings from the fields of art, design, environmental
psychology, and human computer interaction (HCI).
The aims of this research endeavor were to locate answers to the following
questions related to energy conservation in various public contexts. Might dynamic
feedback from data-driven artwork create a better understanding of resource
consumption patterns? Which environments are best for promoting eco-visualisation:
borne, workplace, or alternative spaces? What kinds of visualisation tactics are most
effective in communicating energy consumption data? These initial questions
generated a four-year research project that involved an extensive literature review in
both environmental psychology and art history that culminated in three different case
studies, which targeted the effectiveness of eco-visualisation as an innovative
conservation strategy. The three primary claims to be proven with supporting evidence
from the literature reviews and case studies are: (1) eco-visualisation offers novel visual
ways of making invisible energy data comprehensible, and encourages site-based
learning; (2) eco-visualisation that provides real time visual feedback can increase
environmental awareness and possibly increase the conservation behaviour in the
viewing population; (3) eco-visualisation encourages new perceptions of linkages
between the single individual and a larger community via site-based dialogue and
conversation.
Although the results of the three case studies are generally positive and prove
the claims, there are larger social and environmental questions that will be addressed.
How can eco-visualisation be productively integrated into the home or workplace
without becoming a disposable gadget that represents a passing fad or fancy? Most
importantly, how can energy conservation interventions be conceived to be as
sustainable as possible, and non-threatening from a privacy perspective? These
questions and more contribute to the discussion and analysis of the results of the three
case studies that constitute the primary source of new knowledge asserted here in this
dissertation
Risk? Crisis? Emergency? Implications of the new climate emergency framing for governance and policy
The term “climate emergency” represents a new phase in climate change framing that many hope will invigorate more climate action. Yet there has been relatively little discussion of how the new emergency framing might shape broader governance and policy. In this advanced review, we critically review and synthesize existing literature on crisis and emergency to inform our understanding of how this new shift might affect governance and policy. Specifically, we explore the literature on crisis governance and policy to argue that there is no simple answer to whether the “climate emergency” framing will be supportive of climate governance and policy; rather, more work needs to be done to understand how different political actors respond according to their perceptions, interests and values. To assist this endeavor, we develop a typology of four policy pathways, ranging from “no emergency,” to “no emergency, but recognize risk,” “emergency as a threat” and “emergency as an opportunity.” We highlight the need to consider the effects of multiple and overlapping emergency frames, using the example of the intersection of climate change and COVID-19. Finally, we suggest new interdisciplinary research directions for critically analyzing and refining this new phase of climate change framing
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Implicit Depression and Hopelessness in Remitted Depressed Individuals
Cognitive theories of depression posit that automatically activated cognitive schemas, including negative thoughts about the self and the future, predispose individuals to develop depressive disorders. However, prior research has largely examined these constructs using explicit tests in currently depressed individuals. Using the Implicit Association Test (IAT), the present study examined automatic associations between the self and mood state ("depression IAT") and between the future and mood state ("hopelessness IAT") before and after a negative mood induction in 19 remitted depressed individuals and 23 healthy controls. In the depression IAT, remitted depressed participants exhibited an overall lower tendency to associate themselves with happiness relative to the healthy controls before the mood induction. Control, but not remitted depressed, participants' automatic associations between the self and happiness diminished following the mood induction. Contrary to our hypotheses, no significant findings emerged when considering the hopelessness IAT. Consistent with prior studies, no significant correlations emerged between implicit and explicit biases, suggesting that these measures probe different processes. Results extend prior IAT research by documenting the presence of a reduced tendency to associate the self with happiness in a sample at increased risk for depression.Psycholog
IMP2 Expression In The Mouse Nervous System
Background: Insulin-like growth factor-II (IGF-II) mRNA-binding protein-2 (IMP2) is one of the three homologs (IMP1-3) that play important roles in the posttranscriptional regulation of gene expression in several tissues. IMP1/ZBP1 (zipcode binding protein) has been shown to play important roles in axon guidance and regeneration by regulating the localization and translation of specific mRNAs. However, the function of IMP2 is least understood, largely because an isoform-specific antibody is not available, which makes the conventional techniques to locate protein expression not feasible
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Enhanced Negative Feedback Responses in Remitted Depression
Major depressive disorder (MDD)is characterized by hypersensitivity to negative feedback that might involve frontocingulate dysfunction. MDD patients exhibit enhanced electrophysiological responses to negative internal (errors) and external (feedback) cues. Whether this dysfunction extends to remitted depressed (RD) individuals with a history of MDD is currently unknown. To address this issue, we examined the feedback-related negativity in RD and control participants using a probabilistic punishment learning task. Despite equivalent behavioral performance, RD participants showed larger feedback-related negativities to negative feedback relative to controls; group differences remained after accounting for residual anxiety and depressive symptoms. The present findings suggest that abnormal responses to negative feedback extend to samples at increased risk for depressive episodes in the absence of current symptoms.Psycholog
Prospectus, October 2, 2002
https://spark.parkland.edu/prospectus_2002/1024/thumbnail.jp
Imaginary relish and exquisite torture: The elaborated intrusion theory of desire
The authors argue that human desire involves conscious cognition that has
strong affective connotation and is potentially involved in the determination
of appetitive behavior rather than being epiphenomenal to it. Intrusive
thoughts about appetitive targets are triggered automatically by external or
physiological cues and by cognitive associates. When intrusions elicit
significant pleasure or relief, cognitive elaboration usually ensues.
Elaboration competes with concurrent cognitive tasks through retrieval of
target-related information and its retention in working memory. Sensory
images are especially important products of intrusion and elaboration because
they simulate the sensory and emotional qualities of target acquisition. Desire
images are momentarily rewarding but amplify awareness of somatic and
emotional deficits. Effects of desires on behavior are moderated by competing
incentives, target availability, and skills. The theory provides a coherent
account of existing data and suggests new directions for research and
treatment
Suppression of RAF/MEK or PI3K synergizes cytotoxicity of receptor tyrosine kinase inhibitors in glioma tumor-initiating cells
Additional file 5. Data of RPPA analysis
Effect of Androgen Deprivation Therapy on Bone Mineral Density in a Prostate Cancer Cohort in New Zealand: A Pilot Study
Introduction: Reduction in bone mineral density (BMD) is a common side effect of androgen deprivation therapy (ADT). We aimed to examine the cross-sectional and longitudinal variation in BMD and associated bone markers in patients with nonmetastatic prostate cancer (PCa) managed with and without ADT.
Methods: Bone mineral density of the total body, lumbar spine, femoral neck, ultradistal forearm, and one-third distal radius was measured in 88 patients with PCa without bone metastases at baseline and at 6 months. Patients were categorized into 4 groups: (1) acute ADT (≤6 months), (2) chronic ADT ( > 6 months), (3) former ADT, and (4) no ADT (controls). Serum levels of bone metabolism markers, procollagen type I N-terminal propeptide (PINP) and C-terminal cross-linking telopeptide of type I collagen (CTX), were also measured.
Results: In the cross-sectional analysis, men receiving chronic ADT had significantly lower total body BMD as compared with former ADT users and men with no ADT. In longitudinal analysis, a significant reduction in ultradistal forearm BMD was observed in both acute and chronic ADT users after 6 months (4.08% and 2.7%, P =.012 and.026, respectively). A significant reduction in total body BMD was observed in acute ADT users (2.99%, P =.032). Former ADT users had a significant increase in both lumbar spine and femoral neck BMD (2.84% and 1.59%, P =.008 and.002, respectively). The changes in BMD were not significantly different between acute and chronic ADT users. In the cross-sectional analysis, higher levels of PINP and CTX were observed in acute and chronic ADT users than former ADT users or PCa controls. In longitudinal analysis, the level of serum PINP and CTX did not change significantly from baseline to 6 months in acute, chronic, and former ADT users, or PCa controls, and the percentage change did not differ among the 4 groups.
Conclusions: Men on acute ADT had a similar rate of bone loss to men on chronic ADT. Reversibility in ADT-induced bone loss was observed in those who discontinued ADT. Serum levels of PINP and CTX were higher in acute and chronic ADT users and levels returned to the range of PCa controls when treatment was withdrawn
The role of impulsivity in the aetiology of drug dependence: reward sensitivity versus automaticity
Journal ArticleResearch Support, Non-U.S. Gov'tCopyright © The Author(s) 2011.RATIONALE: Impulsivity has long been known as a risk factor for drug dependence, but the mechanisms underpinning this association are unclear. Impulsivity may confer hypersensitivity to drug reinforcement which establishes higher rates of instrumental drug-seeking and drug-taking behaviour, or may confer a propensity for automatic (non-intentional) control over drug-seeking/taking and thus intransigence to clinical intervention. METHOD: The current study sought to distinguish these two accounts by measuring Barratt Impulsivity and craving to smoke in 100 smokers prior to their completion of an instrumental concurrent choice task for tobacco (to measure the rate of drug-seeking) and an ad libitum smoking test (to measure the rate of drug-taking-number of puffs consumed). RESULTS: The results showed that impulsivity was not associated with higher rates of drug-seeking/taking, but individual differences in smoking uptake and craving were. Rather, nonplanning impulsivity moderated (decreased) the relationship between craving and drug-taking, but not drug-seeking. CONCLUSIONS: These data suggest that whereas the uptake of drug use is mediated by hypervaluation of the drug as an instrumental goal, the orthogonal trait nonplanning impulsivity confers a propensity for automatic control over well-practiced drug-taking behaviour.MR
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